Frontal delta power associated with negative symptoms in ultra-high risk individuals who transitioned to psychosis

S Lavoie; MR Schäfer; TJ Whitford; F Benninger; M Feucht; CM Klier; HP Yuen; C Pantelis; PD McGorry; GP Amminger

Journal article

Frontal delta power associated with negative symptoms in ultra-high risk individuals who transitioned to psychosis

S Lavoie, MR Schäfer, TJ Whitford, F Benninger, M Feucht, CM Klier, HP Yuen, C Pantelis, PD McGorry, GP Amminger

Schizophrenia Research | ELSEVIER SCIENCE BV | Published : 2012

DOI: 10.1016/j.schres.2012.03.033

Abstract

It has recently been shown that treatment with long-chain omega-3 polyunsaturated fatty acids (PUFAs) could decrease the rate of transition to psychosis, and improve psychiatric symptoms and global functioning in people at ultra-high risk (UHR) for psychosis. Previous studies have suggested that resting state brain activity measured with electroencephalography (EEG) may represent an objective biomarker of changes in neural function associated with supplementation with omega-3 PUFAs. It has also been proposed that although resting state EEG cannot, by itself, predict transition to psychosis in UHR individuals, the combination of resting state EEG with negative symptoms may be a valid predicto..

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University of Melbourne Researchers

Suzie Lavoie Author

Thomas Whitford Author

Hok Yuen Author

Christos Pantelis Author

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Grants

Awarded by Stanley Medical Research Institute

Funding Acknowledgements

This research was supported by grant 03T-315 from the Stanley Medical Research Institute to A/Prof G. Paul Amminger. Dr Suzie Lavoie, Prof Christos Pantelis, Prof Patrick McGorry and A/Prof G. Paul Amminger were supported by a National Health and Medical Research Council of Australia (NHMRC) Program Grant (ID: 566529). Prof Christos Pantelis was also supported by a NHMRC Senior Principal Research Fellowship (ID: 628386). Dr Thomas J. Whitford was supported by an overseas-based (CJ Martin) NHMRC Biomedical Training Fellowship (ID: 520627).